|
|
||
|
|
|
|
|
UniProt functional annotation for Q9M6U3 | ||
|
|
|
|
|
|
||
| UniProt code: Q9M6U3. |
|
||
| Organism: | |
Brassica juncea (Indian mustard) (Sinapis juncea). |
| Taxonomy: | |
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica. |
|
||
|
||
| Function: | |
This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. {ECO:0000256|RuleBase:RU364071}. |
|
||
| Catalytic activity: | |
Reaction=acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-hydroxy-3- methylglutaryl-CoA + CoA + H(+); Xref=Rhea:RHEA:10188, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43074, ChEBI:CHEBI:57286, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.3.10; Evidence={ECO:0000256|RuleBase:RU364071}; |
| Pathway: | |
Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3. {ECO:0000256|RuleBase:RU364071}. |
| Similarity: | |
Belongs to the thiolase-like superfamily. HMG-CoA synthase family. {ECO:0000256|ARBA:ARBA00007061, ECO:0000256|RuleBase:RU364071}. |
Annotations taken from UniProtKB at the EBI.