UniProt functional annotation for Q8I3W2

UniProt code: Q8I3W2.

Organism: Plasmodium falciparum (isolate 3D7).
Taxonomy: Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania).
 
Function: Involved in the first step of the non-oxidative branch of the pentose phosphate pathway. It catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. {ECO:0000250|UniProtKB:P0A7Z0}.
 
Catalytic activity: Reaction=aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate; Xref=Rhea:RHEA:14657, ChEBI:CHEBI:58121, ChEBI:CHEBI:58273; EC=5.3.1.6; Evidence={ECO:0000250|UniProtKB:P0A7Z0};
Pathway: Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. {ECO:0000250|UniProtKB:P0A7Z0}.
Subunit: Homodimer. {ECO:0000269|PubMed:16682767}.
Similarity: Belongs to the ribose 5-phosphate isomerase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.