| UniProt functional annotation for P25713 | |||
| UniProt code: P25713. |
| Organism: | Homo sapiens (Human). | |
| Taxonomy: | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. | |
| Function: | Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. | |
| Tissue specificity: | Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain. | |
| Similarity: | Belongs to the metallothionein superfamily. Type 1 family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.