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UniProt functional annotation for O87120 | ||
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| UniProt code: O87120. |
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| Organism: | |
Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Aggregatibacter. |
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| Function: | |
CDTs are cytotoxins which induce host cell distension, growth arrest in G2/M phase, nucleus swelling, and chromatin fragmentation in HeLa cells. {ECO:0000269|PubMed:16434747}. |
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| Subunit: | |
Heterotrimer of 3 subunits, CdtA, CdtB and CdtC. May form higher oligomers. {ECO:0000269|PubMed:11497226, ECO:0000269|PubMed:16434747}. |
| Subcellular location: | |
Cell outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.