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UniProt functional annotation for P24228 | ||
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| UniProt code: P24228. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction. {ECO:0000269|PubMed:2046551}. |
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| Catalytic activity: | |
Reaction=Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.; EC=3.4.16.4; |
| Pathway: | |
Cell wall biogenesis; peptidoglycan biosynthesis. |
| Subcellular location: | |
Periplasm {ECO:0000305}. |
| Miscellaneous: | |
In E.coli there are three murein endopeptidases: two are penicillin sensitive (DacB and PbpG), the other (MepA) not. |
| Similarity: | |
Belongs to the peptidase S13 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.