UniProt functional annotation for P0A108

UniProt code: P0A108.

Organism: Pseudomonas sp. (strain C18).
Taxonomy: Bacteria; Proteobacteria.
 
Function: Involved in the naphthalene catabolic pathway. Catalyzes the meta-cleavage of 1,2-dihydroxynaphthalene (1,2-DHN) to yield 2- hydroxychromene-2-carboxylic acid (By similarity). {ECO:0000250}.
 
Catalytic activity: Reaction=naphthalene-1,2-diol + O2 = 2-hydroxychromene-2-carboxylate + H(+); Xref=Rhea:RHEA:27310, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:17435, ChEBI:CHEBI:59350; EC=1.13.11.56;
Cofactor: Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000269|Ref.2};
Pathway: Aromatic compound metabolism; naphthalene degradation.
Miscellaneous: Encoded on an unnamed 75 kb plasmid. {ECO:0000305|PubMed:8226631}.
Similarity: Belongs to the extradiol ring-cleavage dioxygenase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.