UniProt functional annotation for Q5SI78

UniProt code: Q5SI78.

Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
Taxonomy: Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
 
Catalytic activity: Reaction=H2O + L-arginine = L-ornithine + urea; Xref=Rhea:RHEA:20569, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199, ChEBI:CHEBI:32682, ChEBI:CHEBI:46911; EC=3.5.3.1; Evidence={ECO:0000256|RuleBase:RU361159};
Cofactor: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000256|RuleBase:RU361159}; Note=Binds 2 manganese ions per subunit. {ECO:0000256|RuleBase:RU361159};
Similarity: Belongs to the arginase family. {ECO:0000256|PROSITE- ProRule:PRU00742, ECO:0000256|RuleBase:RU361159}.

Annotations taken from UniProtKB at the EBI.