UniProt functional annotation for P17452

UniProt code: P17452.

Organism: Pasteurella multocida.
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Pasteurella.
 
Function: This is a dermonecrotic toxin. This osteolytic toxin, induces bone resorption. Potent mitogen. This toxin is associated with the severe progressive form of the atrophic rhinitis, a major respiratory disease in pigs.
 
Subcellular location: Cytoplasm {ECO:0000305}. Secreted {ECO:0000305}. Host membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Miscellaneous: Closely spaced cysteine and histidine residues may provide the toxin with an affinity for metal.
Miscellaneous: The sequence shown is that of strain NCTC 12178.

Annotations taken from UniProtKB at the EBI.