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UniProt functional annotation for Q17027 | ||
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| UniProt code: Q17027. |
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| Organism: | |
Anopheles gambiae (African malaria mosquito). |
| Taxonomy: | |
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles. |
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| Function: | |
Responsible for the anti Gram-positive activity of immune hemolymph. {ECO:0000250}. |
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| Subcellular location: | |
Secreted. |
| Developmental stage: | |
In larvae, transcript is enhanced 4 hours after the bacterial infection, increases up to 12 hours post inoculation and declines by 24 hours and by 30 hours returns to background levels. In adult female, expression is evident by 18 hours after infection. Constitutively expressed in both early and late pupae. {ECO:0000269|PubMed:8799739}. |
| Induction: | |
By bacterial infection. {ECO:0000269|PubMed:8799739}. |
| Similarity: | |
Belongs to the invertebrate defensin family. Type 1 subfamily. {ECO:0000255|PROSITE-ProRule:PRU00710}. |
| Sequence caution: | |
Sequence=CAA63775.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.