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UniProt functional annotation for Q9QX73 | ||
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| UniProt code: Q9QX73. |
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| Organism: | |
Rattus norvegicus (Rat). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. |
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| Function: | |
Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters. {ECO:0000269|PubMed:10607391, ECO:0000269|PubMed:11727829, ECO:0000269|PubMed:15215304}. |
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| Subunit: | |
Interacts with GPHN. {ECO:0000269|PubMed:10607391, ECO:0000269|PubMed:11727829, ECO:0000269|PubMed:15215304, ECO:0000269|PubMed:16616186}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:10607391, ECO:0000269|PubMed:11727829, ECO:0000269|PubMed:15215304}. Cell junction, synapse, postsynaptic density {ECO:0000250|UniProtKB:Q3UTH8}. |
| Tissue specificity: | |
Detected in brain, throughout the gray matter. Detected at low levels in heart and skeletal muscle. {ECO:0000269|PubMed:10607391}. |
Annotations taken from UniProtKB at the EBI.