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UniProt functional annotation for O75717 | ||
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| UniProt code: O75717. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. {ECO:0000269|PubMed:19805216}. |
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| Subunit: | |
Interacts with the polymerase alpha catalytic subunit POLA1. Interacts with MCM10. Interacts with DNA2. {ECO:0000269|PubMed:17761813, ECO:0000269|PubMed:22570476}. |
| Subcellular location: | |
Nucleus, nucleoplasm {ECO:0000250}. |
Annotations taken from UniProtKB at the EBI.