UniProt functional annotation for Q9ADP7

UniProt code: Q9ADP7.

Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
Taxonomy: Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
 
Function: Probably regulates the expression of its own gene and the adjacent SCO4007 gene by binding to two operator sites in the SCO4007- SCO4008 intergenic region. {ECO:0000269|PubMed:23831227}.
 
Activity regulation: Binding of a wide range of cationic hydrophobic compounds to SCO4008 causes a decrease in DNA-binding, probably via allosteric conformational change of SCO4008. {ECO:0000269|PubMed:23831227}.
Subunit: Homodimer. Four dimers bind to the two operator sites. {ECO:0000269|PubMed:23831227}.
Induction: Autoregulated. {ECO:0000305|PubMed:23831227}.
Domain: Contains an N-terminal DNA-binding domain and a C-terminal dimerization domain. {ECO:0000269|PubMed:23831227}.

Annotations taken from UniProtKB at the EBI.