UniProt functional annotation for P21564

UniProt code: P21564.

Organism: Torpedo marmorata (Marbled electric ray).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Elasmobranchii; Batoidea; Torpediniformes; Torpedinidae; Torpedo.
 
Function: Voltage-gated chloride channel. This channel is thought to ensure the high conductance of the non-innervated membrane of the electrocyte necessary for efficient current generation caused by sodium influx through the acetylcholine receptor at the innervated membrane.
 
Subunit: Homodimer. Each subunit contains a channel ('Double barreled channel'). {ECO:0000269|PubMed:16472749}.
Subcellular location: Membrane; Multi-pass membrane protein.
Miscellaneous: The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The absence of conserved gating glutamate residues is typical for family members that function as channels (By similarity). {ECO:0000250}.
Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClC-0 subfamily. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.