| UniProt functional annotation for P21564 | |||
| UniProt code: P21564. |
| Organism: | Torpedo marmorata (Marbled electric ray). | |
| Taxonomy: | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Elasmobranchii; Batoidea; Torpediniformes; Torpedinidae; Torpedo. | |
| Function: | Voltage-gated chloride channel. This channel is thought to ensure the high conductance of the non-innervated membrane of the electrocyte necessary for efficient current generation caused by sodium influx through the acetylcholine receptor at the innervated membrane. | |
| Subunit: | Homodimer. Each subunit contains a channel ('Double barreled channel'). {ECO:0000269|PubMed:16472749}. | |
| Subcellular location: | Membrane; Multi-pass membrane protein. | |
| Miscellaneous: | The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The absence of conserved gating glutamate residues is typical for family members that function as channels (By similarity). {ECO:0000250}. | |
| Similarity: | Belongs to the chloride channel (TC 2.A.49) family. ClC-0 subfamily. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.