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UniProt functional annotation for O43312 | ||
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| UniProt code: O43312. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton. |
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| Subunit: | |
Binds to actin. Binds to the cytoplasmic domain of receptor protein tyrosine phosphatase delta. {ECO:0000269|PubMed:12570871}. |
| Subcellular location: | |
Cytoplasm, cytoskeleton. |
| Tissue specificity: | |
Expressed in many tissues, including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood. {ECO:0000269|PubMed:12082544}. |
| Domain: | |
The WH2 motif at the C-terminus binds to actin monomers. |
| Similarity: | |
Belongs to the MTSS family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.