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PDBsum entry 2c8h

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Transferase PDB id
2c8h
Contents
Protein chains
204 a.a.
Ligands
NAD ×2
SO4 ×6
Waters ×714

References listed in PDB file
Key reference
Title Structural properties of wild-Type and two artt motif mutants clostridium botulinum c3 exoenzyme isoform 1 in different substrate complexed states and crystal forms.
Authors E.A.Stura, J.Menetrey, G.Flatau, P.Boquet, A.Menez.
Ref. To be Published ...
Secondary reference #1
Title Nad binding induces conformational changes in rho ADP-Ribosylating clostridium botulinum c3 exoenzyme.
Authors J.Ménétrey, G.Flatau, E.A.Stura, J.B.Charbonnier, F.Gas, J.M.Teulon, M.H.Le du, P.Boquet, A.Menez.
Ref. J Biol Chem, 2002, 277, 30950-30957. [DOI no: 10.1074/jbc.M201844200]
PubMed id 12029083
Full text Abstract
Figure 2.
Fig. 2. Crystal-packing contacts of the constraint ARTT loop conformation. Stereo-view of the constraint ARTT loop conformation from molecule B with its crystal-packing contacts shown in dark and light green, respectively. The NAD-induced ARTT loop conformation from molecule A, superimposed on molecule B is shown in blue. Color code and orientation are the same as in Fig. 1. The side chains of the residues that are involved in steric hindrance are shown as ball-and-stick representations.
Figure 5.
Fig. 5. Crab-claw movement. The overall structure of C3-NAD (molecule A) is shown in a curved line with a ball-and-stick representation of NAD. Superimposition of the crab-claw subdomains is shown with the NAD-bound molecule A in blue, the unbound molecule A in cream, and the ADP-bound molecule D in red. The color code is the same as in the previous figures.
The above figures are reproduced from the cited reference with permission from the ASBMB
PROCHECK
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