UniProt functional annotation for Q8IAY6

UniProt code: Q8IAY6.

Organism: Plasmodium falciparum (isolate 3D7).
Taxonomy: Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania).
 
Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
 
Catalytic activity: Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:18421; EC=1.15.1.1; Evidence={ECO:0000269|PubMed:17020617};
Cofactor: Name=Fe cation; Xref=ChEBI:CHEBI:24875; Note=Binds 1 Fe cation per subunit.;
Subunit: Homodimer. {ECO:0000269|PubMed:17020617}.
Subcellular location: Cytoplasm {ECO:0000305}.
Similarity: Belongs to the iron/manganese superoxide dismutase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.