UniProt functional annotation for O30033

UniProt code: O30033.

Organism: Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126).
Taxonomy: Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae; Archaeoglobus.
 
Function: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs (Probable). {ECO:0000305|PubMed:16285927, ECO:0000305|PubMed:20392821}.
 
Subunit: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with a hexameric ring- like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG (Probable). {ECO:0000305|PubMed:16285927, ECO:0000305|PubMed:20392821}.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00975}.
Domain: Contains an N-terminal domain that mediates interactions with the hexameric ring, a central S1 domain and a C-terminal zinc-ribbon domain. {ECO:0000269|PubMed:16285927}.
Miscellaneous: The zinc ion has probably a structural role. {ECO:0000305|PubMed:16285927}.
Similarity: Belongs to the CSL4 family. {ECO:0000255|HAMAP- Rule:MF_00975}.

Annotations taken from UniProtKB at the EBI.