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UniProt functional annotation for Q6QLQ5 | ||
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| UniProt code: Q6QLQ5. |
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| Organism: | |
Gallus gallus (Chicken). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus. |
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| Function: | |
Binds bacterial lipopolysaccharide (LPS). Has potent antimicrobial activity against Gram-positive and Gram-negative bacteria (in vitro). Has hemolytic activity (in vitro). May play a role in the innate immune response. {ECO:0000269|PubMed:16326712, ECO:0000269|PubMed:16817888}. |
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| Subcellular location: | |
Secreted {ECO:0000305}. |
| Tissue specificity: | |
Detected in gizzard, liver, small intestine, large intestine, cloaca, bursa of Fabricius, gall bladder, lung, trachea, kidney, testis and bone marrow. {ECO:0000269|PubMed:15148642, ECO:0000269|PubMed:17827276}. |
| Similarity: | |
Belongs to the cathelicidin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.