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PDBsum entry 2amm
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Transport protein
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PDB id
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2amm
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References listed in PDB file
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Key reference
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Title
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Crystal structures, Ligand induced conformational change and heme deformation in complexes of nitrophorin 2, A nitric oxide transport protein from rhodnius prolixus
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Authors
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A.Weichsel,
R.E.Berry,
F.A.Walker,
W.R.Montfort.
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Ref.
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To be Published ...
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Secondary reference #1
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Title
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The crystal structure of nitrophorin 2. A trifunctional antihemostatic protein from the saliva of rhodnius prolixus.
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Authors
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J.F.Andersen,
W.R.Montfort.
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Ref.
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J Biol Chem, 2000,
275,
30496-30503.
[DOI no: ]
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PubMed id
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Figure 3.
Fig. 3. Ribbon diagram of the NP2 structure. The eight
strands of the  -barrel are
labeled A-H, and the heme, bound in the central cavity of the
protein, is shown in black.
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Figure 4.
Fig. 4. Detail of the heme-binding region of NP2. The
view is from the back of the heme pocket. Hydrophobic residues
lining the distal pocket are shown along with the distal ligand
(either ammonia or water). On the proximal side of the heme, the
ligand His^57 is shown along with the hydrogen bonding network
involving Asn^67 and an intervening water molecule. Residues
hydrogen bonding with the heme propionate groups are also shown.
Oxygens are indicated by stippled spheres, and nitrogens are
indicated by larger open spheres.
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The above figures are
reproduced from the cited reference
with permission from the ASBMB
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