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UniProt functional annotation for P01887 | ||
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| UniProt code: P01887. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. |
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| Subunit: | |
Heterodimer of an alpha chain and a beta chain. Beta-2- microglobulin is the beta-chain of major histocompatibility complex class I molecules. Forms a heterotrimer with MR1 and a metabolite antigen. {ECO:0000250|UniProtKB:P61769}. |
| Subcellular location: | |
Secreted. |
| Polymorphism: | |
The following alleles of B2M are known: A, B, W2, W3, W4 and W5 (C). The sequence shown is that of allele B. {ECO:0000305}. |
| Similarity: | |
Belongs to the beta-2-microglobulin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.