UniProt functional annotation for P81461



	UniProt functional annotation for P81461

UniProt code: P81461.

Organism: Canavalia cathartica (Jackbean) (Canavalia virosa).

Taxonomy: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade; NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Canavalia.

Function: Glucose/D-mannose specific lectin. {ECO:0000269|PubMed:25860443, ECO:0000269|Ref.3}.

Subunit: Homotetramer. {ECO:0000269|PubMed:25860443, ECO:0000269|Ref.3}.

Ptm: Concanavalin A-like lectins of the Diocleinae subtribe undergo proteolytic processing referred to as circular permutation. The propeptide is split into an N-terminal and a C-terminal part, the gamma and beta chain, respectively. These are then religated in beta-gamma order to form the mature alpha chain. The beta and gamma chains can often be detected in cell extracts (By similarity). Residues 1-118 of the mature chain, as displayed here, probably constitute the beta chain in the propeptide, residues 119-237 the gamma chain (Probable). {ECO:0000250|UniProtKB:C0HK27, ECO:0000305}.

Miscellaneous: Binds one manganese (or another transition metal) ion and one calcium ion. The metal ions are essential for the saccharide- binding and cell-agglutinating activities. {ECO:0000305|PubMed:17327674}.

Similarity: Belongs to the leguminous lectin family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.


Organism:		Canavalia cathartica (Jackbean) (Canavalia virosa).
Taxonomy:		Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade; NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Canavalia.



Function:		Glucose/D-mannose specific lectin. {ECO:0000269\|PubMed:25860443, ECO:0000269\|Ref.3}.


Subunit:		Homotetramer. {ECO:0000269\|PubMed:25860443, ECO:0000269\|Ref.3}.
Ptm:		Concanavalin A-like lectins of the Diocleinae subtribe undergo proteolytic processing referred to as circular permutation. The propeptide is split into an N-terminal and a C-terminal part, the gamma and beta chain, respectively. These are then religated in beta-gamma order to form the mature alpha chain. The beta and gamma chains can often be detected in cell extracts (By similarity). Residues 1-118 of the mature chain, as displayed here, probably constitute the beta chain in the propeptide, residues 119-237 the gamma chain (Probable). {ECO:0000250\|UniProtKB:C0HK27, ECO:0000305}.
Miscellaneous:		Binds one manganese (or another transition metal) ion and one calcium ion. The metal ions are essential for the saccharide- binding and cell-agglutinating activities. {ECO:0000305\|PubMed:17327674}.
Similarity:		Belongs to the leguminous lectin family. {ECO:0000305}.