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UniProt functional annotation for P43555 | ||
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| UniProt code: P43555. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Involved in the secretion of glycoproteins and in nucleus architecture and gene silencing. Required for the endoplasmic reticulum exit of EMP46. {ECO:0000269|PubMed:12134087, ECO:0000269|PubMed:14627716}. |
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| Subunit: | |
Homooligomers. Interacts with EMP46 in the endoplasmic reticulum membrane. Interacts with the coatomer proteins COP1, SEC21 and SEC23. {ECO:0000269|PubMed:12857885}. |
| Subcellular location: | |
Golgi apparatus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
| Domain: | |
The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins. {ECO:0000250}. |
| Miscellaneous: | |
Present with 2900 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the EMP46/EMP47 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.