UniProt functional annotation for Q9RVD6

UniProt code: Q9RVD6.

Organism:		Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
Taxonomy:		Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae; Deinococcus.
Function:		Catalyzes the formation of 5'adenyl-Trp and tRNA(Trp) but with 5-fold less activity than TrpRS. Increases the solubility of the nitric oxide synthase oxygenase (nos), as well as its affinity for substrate L-arginine and its nitric-oxide synthase activity. The complex between trpS2 and nos catalyzes the regioselective nitration of tryptophan at the 4-position. {ECO:0000269|PubMed:15520379}.
Catalytic activity:		Reaction=ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L- tryptophanyl-tRNA(Trp); Xref=Rhea:RHEA:24080, Rhea:RHEA-COMP:9671, Rhea:RHEA-COMP:9705, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57912, ChEBI:CHEBI:78442, ChEBI:CHEBI:78535, ChEBI:CHEBI:456215; EC=6.1.1.2;
Subunit:		Homodimer. Forms a complex with nos; one homodimer of trpS2 binds one homodimer of nos.
Induction:		The level of expression increases 2.2-fold, 5 hours after exposure to radiation, and returns to near a base line 5 hours later.
Miscellaneous:		This protein may not be involved in protein biosynthesis.
Similarity:		Belongs to the class-I aminoacyl-tRNA synthetase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.