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UniProt functional annotation for A5K2B2 | ||
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| UniProt code: A5K2B2. |
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| Organism: | |
Plasmodium vivax (strain Salvador I). |
| Taxonomy: | |
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Plasmodium). |
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| Catalytic activity: | |
Reaction=7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8- tetrahydropterin + H(+) + triphosphate; Xref=Rhea:RHEA:22048, ChEBI:CHEBI:15378, ChEBI:CHEBI:18036, ChEBI:CHEBI:58462, ChEBI:CHEBI:136564; EC=4.2.3.12; Evidence={ECO:0000256|ARBA:ARBA00000819}; |
| Cofactor: | |
Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000256|ARBA:ARBA00001947}; |
| Pathway: | |
Cofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3. {ECO:0000256|ARBA:ARBA00005126}. |
| Subunit: | |
Homohexamer formed of two homotrimers in a head to head fashion. {ECO:0000256|ARBA:ARBA00011295}. |
| Similarity: | |
Belongs to the PTPS family. {ECO:0000256|ARBA:ARBA00009164}. |
Annotations taken from UniProtKB at the EBI.