UniProt functional annotation for P13036



	UniProt functional annotation for P13036

UniProt code: P13036.

Organism: Escherichia coli (strain K12).

Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.

Function: FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system.

Subcellular location: Cell outer membrane.

Induction: For induction, the TonB and the ExbB proteins have to be active. Regulation by the iron level mediated by the Fur protein and induction by citrate plus iron suggest that the Fe(3+) dicitrate complex must enter the periplasm where it binds to a transmembrane protein, which regulates transcription of the fec genes directly or via a further inductor. Induced 2-fold by hydroxyurea (PubMed:20005847). {ECO:0000269|PubMed:20005847}.

Similarity: Belongs to the TonB-dependent receptor family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.


Organism:		Escherichia coli (strain K12).
Taxonomy:		Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.



Function:		FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system.


Subcellular location:		Cell outer membrane.
Induction:		For induction, the TonB and the ExbB proteins have to be active. Regulation by the iron level mediated by the Fur protein and induction by citrate plus iron suggest that the Fe(3+) dicitrate complex must enter the periplasm where it binds to a transmembrane protein, which regulates transcription of the fec genes directly or via a further inductor. Induced 2-fold by hydroxyurea (PubMed:20005847). {ECO:0000269\|PubMed:20005847}.
Similarity:		Belongs to the TonB-dependent receptor family. {ECO:0000305}.