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UniProt functional annotation for P59666 | ||
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| UniProt code: P59666. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. {ECO:0000269|PubMed:15616305, ECO:0000269|PubMed:15894545, ECO:0000269|PubMed:17452329, ECO:0000269|PubMed:2006422}. |
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| Subunit: | |
Dimer. {ECO:0000269|PubMed:17452329, ECO:0000269|PubMed:2006422}. |
| Subcellular location: | |
Secreted. |
| Similarity: | |
Belongs to the alpha-defensin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.