UniProt functional annotation for Q9X112

UniProt code: Q9X112.

Organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8).
Taxonomy: Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
 
Function: Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation. {ECO:0000250}.
 
Catalytic activity: Reaction=5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L- methionine + tetrahydropteroyltri-L-glutamate; Xref=Rhea:RHEA:21196, ChEBI:CHEBI:57844, ChEBI:CHEBI:58140, ChEBI:CHEBI:58199, ChEBI:CHEBI:58207; EC=2.1.1.14;
Cofactor: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 1 zinc ion per subunit. {ECO:0000250};
Pathway: Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.
Similarity: Belongs to the vitamin-B12 independent methionine synthase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.