| UniProt functional annotation for Q9X112 | |||
| UniProt code: Q9X112. |
| Organism: | Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8). | |
| Taxonomy: | Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga. | |
| Function: | Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation. {ECO:0000250}. | |
| Catalytic activity: | Reaction=5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L- methionine + tetrahydropteroyltri-L-glutamate; Xref=Rhea:RHEA:21196, ChEBI:CHEBI:57844, ChEBI:CHEBI:58140, ChEBI:CHEBI:58199, ChEBI:CHEBI:58207; EC=2.1.1.14; | |
| Cofactor: | Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 1 zinc ion per subunit. {ECO:0000250}; | |
| Pathway: | Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1. | |
| Similarity: | Belongs to the vitamin-B12 independent methionine synthase family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.