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UniProt functional annotation for O25096 | ||
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| UniProt code: O25096. |
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| Organism: | |
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori). |
| Taxonomy: | |
Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter. |
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| Function: | |
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. {ECO:0000255|HAMAP- Rule:MF_00193}. |
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| Catalytic activity: | |
Reaction=ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+); Xref=Rhea:RHEA:21188, ChEBI:CHEBI:15378, ChEBI:CHEBI:28938, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57540, ChEBI:CHEBI:58437, ChEBI:CHEBI:456215; EC=6.3.1.5; Evidence={ECO:0000255|HAMAP-Rule:MF_00193}; |
| Pathway: | |
Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1. {ECO:0000255|HAMAP- Rule:MF_00193}. |
| Subunit: | |
Homodimer. {ECO:0000255|HAMAP-Rule:MF_00193, ECO:0000269|PubMed:15645437}. |
| Similarity: | |
Belongs to the NAD synthetase family. {ECO:0000255|HAMAP- Rule:MF_00193, ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.