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UniProt functional annotation for P0A715 | ||
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| UniProt code: P0A715. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth. |
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| Catalytic activity: | |
Reaction=D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy- alpha-D-manno-2-octulosonate-8-phosphate + phosphate; Xref=Rhea:RHEA:14053, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:57693, ChEBI:CHEBI:58702, ChEBI:CHEBI:85985; EC=2.5.1.55; |
| Pathway: | |
Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. |
| Pathway: | |
Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. |
| Subunit: | |
Homotrimer. |
| Subcellular location: | |
Cytoplasm. |
| Mass spectrometry: | |
Mass=30842; Mass_error=17; Method=Electrospray; Evidence={ECO:0000269|PubMed:11371194}; |
| Similarity: | |
Belongs to the KdsA family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.