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UniProt functional annotation for Q9CZG9 | ||
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| UniProt code: Q9CZG9. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
Mediates docking of ADAM10 to zonula adherens by interacting with PLEKHA7 which is required for PLEKHA7 to interact with the ADAM10- binding protein TSPAN33. {ECO:0000269|PubMed:30463011}. |
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| Subunit: | |
Interacts with ATP2B1, ATP2B2, ATP2B3, ATP2B4 and ATP7A (By similarity). Interacts with PLEKHA7 (via WW domains) at zonula adherens; this interaction is essential for the interaction between PLEKHA7 and the ADAM10-binding protein TSPAN33 (PubMed:30463011). Interacts with SLC5A6 (By similarity). {ECO:0000250|UniProtKB:Q5EBL8, ECO:0000269|PubMed:30463011}. |
| Subcellular location: | |
Cytoplasm {ECO:0000250|UniProtKB:Q5EBL8}. Cell junction, adherens junction {ECO:0000269|PubMed:30463011}. Cell membrane {ECO:0000269|PubMed:30463011}. |
Annotations taken from UniProtKB at the EBI.