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UniProt functional annotation for Q800Y1 | ||
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| UniProt code: Q800Y1. |
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| Organism: | |
Argyrosomus regius (Meagre). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Sciaenidae; Argyrosomus. |
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| Function: | |
Binds strongly to apatite and calcium. {ECO:0000250}. |
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| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
In the branchial arches, BGP is found outside the chondrocyte-containing zone. It is found in some cells in the basal zone of the branchial filaments, near the branchial arches, and within the extracellular matrix in the medial zone. In the vertebra, BGP is found in the mineralized bone matrix. {ECO:0000269|PubMed:12568402}. |
| Ptm: | |
Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. {ECO:0000255|PROSITE-ProRule:PRU00463, ECO:0000269|PubMed:14668966, ECO:0000269|PubMed:15667217}. |
| Similarity: | |
Belongs to the osteocalcin/matrix Gla protein family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.