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PDBsum entry 1vq0
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References listed in PDB file
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Key reference
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Title
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Crystal structure of hsp33 chaperone (tm1394) from thermotoga maritima at 2.20 a resolution.
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Authors
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L.Jaroszewski,
R.Schwarzenbacher,
D.Mcmullan,
P.Abdubek,
S.Agarwalla,
E.Ambing,
H.Axelrod,
T.Biorac,
J.M.Canaves,
H.J.Chiu,
A.M.Deacon,
M.Didonato,
M.A.Elsliger,
A.Godzik,
C.Grittini,
S.K.Grzechnik,
J.Hale,
E.Hampton,
G.W.Han,
J.Haugen,
M.Hornsby,
H.E.Klock,
E.Koesema,
A.Kreusch,
P.Kuhn,
S.A.Lesley,
M.D.Miller,
K.Moy,
E.Nigoghossian,
J.Paulsen,
K.Quijano,
R.Reyes,
C.Rife,
G.Spraggon,
R.C.Stevens,
H.Van den bedem,
J.Velasquez,
J.Vincent,
A.White,
G.Wolf,
Q.Xu,
K.O.Hodgson,
J.Wooley,
I.A.Wilson.
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Ref.
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Proteins, 2005,
61,
669-673.
[DOI no: ]
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PubMed id
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Abstract
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No abstract given.
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Figure 1.
Figure 1. Crystal structure of Hsp33 from Thermotoga maritima.
(A) Diagram showing the secondary structure elements in TM1394
(chain A) superimposed on its primary sequence. The  -helices,
3[10]-helix,  -bulges,
and  -turns
are indicated. The -sheet
strands are indicated by red letters (A, B, and C). -Hairpins
are depicted as red loops, and cysteine residues coordinating
the zinc are marked with blue dots. No electron density was
found for residues 288-290 as indicated by purple dots. (B)
Stereo ribbon diagram of TM1394 color-coded from N-terminus
(blue) to C-terminus (red), showing the domain organization.
Helices (H1-H10) and -strands
( 1-
13)
are indicated.
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Figure 2.
Figure 2. (A) TM1394 C-terminal zinc-finger domain in ribbon
representation with zinc (pink sphere) and coordinating cysteine
residues (Cys231, Cys233, Cys263, and Cys266) depicted in
sticks. (B) Superposition of the TM1394 crystallographic dimer
(gray) with the biological dimer of oxidized Hsp33 from E. coli
(chain A, blue; chain B, orange) that contains the domain swap
for residues 178-233. (C) Superposition of zinc sites in TM1394
and Hsp33 from Bacillus subtilis (gray with labels in brackets).
Zn^2+ ions are shown as spheres, and the cysteines, as well as
Tyr270(275) and Arg84(86) residues, are depicted in sticks.
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The above figures are
reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2005,
61,
669-673)
copyright 2005.
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