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UniProt functional annotation for P0C1V0 | ||
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| UniProt code: P0C1V0. |
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| Organism: | |
Staphylococcus aureus. |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus. |
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| Function: | |
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity). Specific for fully assembled 70S ribosomes (PubMed:23150671). {ECO:0000255|HAMAP-Rule:MF_00658, ECO:0000269|PubMed:23150671}. |
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| Catalytic activity: | |
Reaction=pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L- homocysteine; Xref=Rhea:RHEA:42752, Rhea:RHEA-COMP:10221, Rhea:RHEA- COMP:10222, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:65314, ChEBI:CHEBI:74486; EC=2.1.1.177; Evidence={ECO:0000255|HAMAP-Rule:MF_00658}; |
| Subunit: | |
Homodimer. {ECO:0000255|HAMAP-Rule:MF_00658, ECO:0000269|PubMed:23150671}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00658}. |
| Similarity: | |
Belongs to the RNA methyltransferase RlmH family. {ECO:0000255|HAMAP-Rule:MF_00658}. |
Annotations taken from UniProtKB at the EBI.