|
|
||
|
|
|
|
|
UniProt functional annotation for P33643 | ||
|
|
|
|
|
|
||
| UniProt code: P33643. |
|
||
| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
|
||
|
||
| Function: | |
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA. Isomerization occurs as a late step during the assembly of the large ribosomal subunit. {ECO:0000269|PubMed:11087118, ECO:0000269|PubMed:17937767}. |
|
||
| Catalytic activity: | |
Reaction=uridine(1911/1915/1917) in 23S rRNA = pseudouridine(1911/1915/1917) in 23S rRNA; Xref=Rhea:RHEA:42524, Rhea:RHEA-COMP:10097, Rhea:RHEA-COMP:10098, ChEBI:CHEBI:65314, ChEBI:CHEBI:65315; EC=5.4.99.23; Evidence={ECO:0000269|PubMed:11087118, ECO:0000269|PubMed:17937767}; |
| Similarity: | |
Belongs to the pseudouridine synthase RluA family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=X57620; Type=Frameshift; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.