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UniProt functional annotation for O58307 | ||
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| UniProt code: O58307. |
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| Organism: | |
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3). |
| Taxonomy: | |
Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus. |
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| Function: | |
Functions in trans to edit the amino acid moiety from mischarged charged Ser-tRNA(Ala). Has little activity against Gly- tRNA(Ala). |
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| Cofactor: | |
Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000269|PubMed:16087889, ECO:0000269|PubMed:16374837}; Note=Binds 1 zinc ion per subunit; the homodimer seems not to bind zinc. The zinc is probably not catalytic (PubMed:16087889). Another report suggests the zinc is catalytic (PubMed:16374837). {ECO:0000269|PubMed:16087889, ECO:0000269|PubMed:16374837}; |
| Subunit: | |
Monomer and homodimer; the dimer is less active in tRNA editing and does not have a zinc ion associated with it (PubMed:16087889). Another report shows only a monomeric form (PubMed:16374837). {ECO:0000269|PubMed:16087889, ECO:0000269|PubMed:16374837}. |
| Subcellular location: | |
Cytoplasm {ECO:0000305}. |
| Similarity: | |
Belongs to the class-II aminoacyl-tRNA synthetase family. Editing domain AlaX-S subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.