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PDBsum entry 1v0m
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Contents |
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* Residue conservation analysis
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References listed in PDB file
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Key reference
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Title
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Atomic resolution analyses of the binding of xylobiose-Derived deoxynojirimycin and isofagomine to xylanase xyn10a.
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Authors
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T.M.Gloster,
S.J.Williams,
S.Roberts,
C.A.Tarling,
J.Wicki,
S.G.Withers,
G.J.Davies.
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Ref.
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Chem Commun (camb), 2004,
16,
1794-1795.
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PubMed id
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Abstract
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The atomic resolution structures of xylobiose-derived isofagomine and
xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A from
Streptomyces lividans reveal undistorted (4)C(1) chair conformed sugars and, in
the case of the deoxynojirimycin analogue, suggest unusual pK(a) changes of the
enzyme's catalytic machinery upon binding.
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