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UniProt functional annotation for P9WIQ1 | ||
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| UniProt code: P9WIQ1. |
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| Organism: | |
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). |
| Taxonomy: | |
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. |
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| Function: | |
Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is a key building block for cell wall construction in Mycobacterium tuberculosis. {ECO:0000269|PubMed:9692181}. |
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| Catalytic activity: | |
Reaction=UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose; Xref=Rhea:RHEA:24132, ChEBI:CHEBI:66914, ChEBI:CHEBI:66915; EC=5.4.99.9; |
| Cofactor: | |
Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000269|PubMed:15843027}; |
| Pathway: | |
Cell wall biogenesis; cell wall polysaccharide biosynthesis. |
| Subunit: | |
Homotetramer. {ECO:0000269|PubMed:15843027}. |
| Similarity: | |
Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.