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UniProt functional annotation for O54788 | ||
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| UniProt code: O54788. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. |
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| Activity regulation: | |
Inhibited by DFFA (DFF45). |
| Subunit: | |
Heterodimer of DFFA and DFFB (By similarity). Interacts with H1-1 (By similarity). {ECO:0000250|UniProtKB:O76075}. |
| Subcellular location: | |
Cytoplasm. Nucleus. |
Annotations taken from UniProtKB at the EBI.