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UniProt functional annotation for P18548 | ||
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| UniProt code: P18548. |
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| Organism: | |
Streptomyces clavuligerus. |
| Taxonomy: | |
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces. |
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| Function: | |
Catalyzes the step from penicillin N to deacetoxy- cephalosporin C. |
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| Catalytic activity: | |
Reaction=2-oxoglutarate + O2 + penicillin N = CO2 + deacetoxycephalosporin C + H2O + succinate; Xref=Rhea:RHEA:20748, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16526, ChEBI:CHEBI:16810, ChEBI:CHEBI:30031, ChEBI:CHEBI:58408, ChEBI:CHEBI:58415; EC=1.14.20.1; |
| Cofactor: | |
Name=Fe cation; Xref=ChEBI:CHEBI:24875; |
| Cofactor: | |
Name=L-ascorbate; Xref=ChEBI:CHEBI:38290; |
| Pathway: | |
Antibiotic biosynthesis; cephalosporin C biosynthesis. |
| Similarity: | |
Belongs to the iron/ascorbate-dependent oxidoreductase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.