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UniProt functional annotation for Q06174 | ||
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| UniProt code: Q06174. |
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| Organism: | |
Geobacillus stearothermophilus (Bacillus stearothermophilus). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus. |
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| Function: | |
Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones. |
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| Catalytic activity: | |
Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+); Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1; Evidence={ECO:0000269|PubMed:15033540}; |
| Biophysicochemical properties: | |
Kinetic parameters: KM=2.16 uM for p-nitrophenyl caproate (at 60 degrees Celsius) {ECO:0000269|PubMed:15033540}; pH dependence: Optimum pH is 9. {ECO:0000269|PubMed:15033540}; Temperature dependence: Optimum temperature is 70 degrees Celsius. {ECO:0000269|PubMed:15033540}; |
| Subunit: | |
Homodimer. {ECO:0000269|PubMed:15033540, ECO:0000269|PubMed:15327954}. |
| Similarity: | |
Belongs to the lipase/esterase LIP3/BchO family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=AAN81911.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA02182.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.