UniProt functional annotation for P00998

UniProt code: P00998.

Organism: Sus scrofa (Pig).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
 
Function: Serine protease inhibitor which exhibits anti-trypsin activity (PubMed:5466061). In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). {ECO:0000250|UniProtKB:P09036, ECO:0000269|PubMed:5466061}.
 
Function: In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production. {ECO:0000250|UniProtKB:P09036}.
 
Subcellular location: Secreted {ECO:0000269|PubMed:5466061, ECO:0000269|PubMed:7169635}.

Annotations taken from UniProtKB at the EBI.