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UniProt functional annotation for P27731 | ||
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| UniProt code: P27731. |
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| Organism: | |
Gallus gallus (Chicken). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus. |
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| Function: | |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. {ECO:0000269|PubMed:1833190}. |
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| Subunit: | |
Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. {ECO:0000269|PubMed:1833190, ECO:0000269|PubMed:8612621}. |
| Subcellular location: | |
Secreted {ECO:0000269|PubMed:1833190, ECO:0000269|PubMed:8612621}. |
| Tissue specificity: | |
Detected in serum (at protein level). Detected in liver and choroid plexus. {ECO:0000269|PubMed:1799976, ECO:0000269|PubMed:1833190, ECO:0000269|PubMed:8612621}. |
| Similarity: | |
Belongs to the transthyretin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.