UniProt functional annotation for P68262

UniProt code: P68262.

Organism: Staphylococcus aureus.
Taxonomy: Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus.
 
Function: Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA. Binds DNA as a dimer (By similarity). {ECO:0000250}.
 
Subunit: Monomer and homodimer. {ECO:0000250}.
Subcellular location: Cytoplasm {ECO:0000305}.
Ptm: Upon exposure to beta-lactams, proteolytic cleavage at a single site impairs dimerization and abolishes repressor activity. {ECO:0000250}.
Similarity: Belongs to the BlaI transcriptional regulatory family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.