| UniProt functional annotation for P68262 | |||
| UniProt code: P68262. |
| Organism: | Staphylococcus aureus. | |
| Taxonomy: | Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus. | |
| Function: | Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA. Binds DNA as a dimer (By similarity). {ECO:0000250}. | |
| Subunit: | Monomer and homodimer. {ECO:0000250}. | |
| Subcellular location: | Cytoplasm {ECO:0000305}. | |
| Ptm: | Upon exposure to beta-lactams, proteolytic cleavage at a single site impairs dimerization and abolishes repressor activity. {ECO:0000250}. | |
| Similarity: | Belongs to the BlaI transcriptional regulatory family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.