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UniProt functional annotation for P13123 | ||
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| UniProt code: P13123. |
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| Organism: | |
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770). |
| Taxonomy: | |
Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus. |
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| Function: | |
Can constrain negative DNA supercoils. May be involved in maintaining the integrity of the genome at high temperature. {ECO:0000250|UniProtKB:P61990}. |
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| Biophysicochemical properties: | |
pH dependence: Highly stable from pH 0 to pH 12. {ECO:0000269|PubMed:27853299}; Temperature dependence: Hyperthermostable. {ECO:0000269|PubMed:27853299}; |
| Subunit: | |
Monomer. {ECO:0000269|PubMed:27853299}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:27853299}. |
| Ptm: | |
Lys-5 was 70% monomethylated in form 7a, 25% in form 7b, and 20% in form 7d. Lys-7 was 50% monomethylated in form 7a, 40% in form 7b, and 50% in form 7d. {ECO:0000269|PubMed:3130377}. |
| Miscellaneous: | |
Sac7a and Sac7b are truncated versions of the Sac7d protein, most likely resulting from post-translational processing, or degradation during isolation. {ECO:0000305|PubMed:7632679}. |
| Similarity: | |
Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.