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UniProt functional annotation for P33883 | ||
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| UniProt code: P33883. |
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| Organism: | |
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas. |
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| Function: | |
Required for the synthesis of PAI consisting of 3-oxo-N- (tetrahydro-2-oxo-3-furanyl)-dodecanamide also known as N-(3- oxododecanoyl)homoserine lactone, an autoinducer molecule which binds to LasR and thus acts in elastase biosynthesis regulation. |
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| Catalytic activity: | |
Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L- homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine; Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685, Rhea:RHEA-COMP:14125, ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:55474, ChEBI:CHEBI:59789, ChEBI:CHEBI:64479, ChEBI:CHEBI:138651; EC=2.3.1.184; |
| Similarity: | |
Belongs to the autoinducer synthase family. {ECO:0000255|PROSITE-ProRule:PRU00533}. |
Annotations taken from UniProtKB at the EBI.