UniProt functional annotation for Q05783

UniProt code: Q05783.

Organism: Drosophila melanogaster (Fruit fly).
Taxonomy: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
 
Function: Binds preferentially single-stranded DNA and unwinds double- stranded DNA. Prefers sites containing the sequence 5'-ttg-3'. Facilitates DNA bending. Associated with early embryonic chromatin in the absence of histone H1. {ECO:0000269|PubMed:1373803, ECO:0000269|PubMed:7720717, ECO:0000269|PubMed:8168480}.
 
Subcellular location: Nucleus. Chromosome.
Developmental stage: Present in all stages of development. {ECO:0000269|PubMed:1373803}.
Similarity: Belongs to the HMGB family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.