UniProt functional annotation for P17596

UniProt code: P17596.

Organism:		Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes).
Taxonomy:		Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Wolinella.
Function:		The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor. {ECO:0000269|PubMed:10586875, ECO:0000269|PubMed:11248702, ECO:0000269|PubMed:9492313}.
Catalytic activity:		Reaction=a menaquinone + succinate = a menaquinol + fumarate; Xref=Rhea:RHEA:27834, Rhea:RHEA-COMP:9537, Rhea:RHEA-COMP:9539, ChEBI:CHEBI:16374, ChEBI:CHEBI:18151, ChEBI:CHEBI:29806, ChEBI:CHEBI:30031; EC=1.3.5.4; Evidence={ECO:0000250|UniProtKB:P0AC47};
Cofactor:		Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:49601; Evidence={ECO:0000269|PubMed:10586875, ECO:0000269|PubMed:11248702}; Note=Binds 1 [2Fe-2S] cluster. {ECO:0000269|PubMed:10586875, ECO:0000269|PubMed:11248702};
Cofactor:		Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137; Evidence={ECO:0000269|PubMed:10586875, ECO:0000269|PubMed:11248702}; Note=Binds 1 [3Fe-4S] cluster. {ECO:0000269|PubMed:10586875, ECO:0000269|PubMed:11248702};
Cofactor:		Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000269|PubMed:10586875, ECO:0000269|PubMed:11248702}; Note=Binds 1 [4Fe-4S] cluster. {ECO:0000269|PubMed:10586875, ECO:0000269|PubMed:11248702};
Subunit:		Part of an enzyme complex containing three subunits: a flavoprotein (frdA), an iron-sulfur protein (frdB), and diheme cytochrome b (frdC). {ECO:0000269|PubMed:10586875}.
Subcellular location:		Cell inner membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305|PubMed:10586875}; Cytoplasmic side {ECO:0000305|PubMed:10586875}.
Similarity:		Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.