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UniProt functional annotation for P14677 | ||
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| UniProt code: P14677. |
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| Organism: | |
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus. |
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| Function: | |
Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactams inactivate the PBPs by acylating an essential serine residue in the active site of these proteins. |
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| Subcellular location: | |
Cell membrane; Single-pass membrane protein. |
| Miscellaneous: | |
The mature form of PBP2x contains an unprocessed signal sequence followed by a membrane-anchoring segment. |
| Similarity: | |
Belongs to the transpeptidase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.