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UniProt functional annotation for P02777 | ||
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| UniProt code: P02777. |
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| Organism: | |
Bos taurus (Bovine). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos. |
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| Function: | |
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation. |
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| Subunit: | |
Homotetramer. |
| Subcellular location: | |
Secreted. |
| Ptm: | |
O-linked glycan consists of Gal-GalNAc disaccharide which is modified with sialic acid residues (microheterogeneity). {ECO:0000269|PubMed:2914894}. |
| Similarity: | |
Belongs to the intercrine alpha (chemokine CxC) family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.