UniProt functional annotation for P29549

UniProt code: P29549.

Organism: Sterkiella nova (Ciliate) (Oxytricha nova).
Taxonomy: Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea; Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Sterkiella.
 
Function: May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
 
Subunit: Heterodimer of an alpha and a beta subunit.
Subcellular location: Nucleus. Chromosome, telomere.
Miscellaneous: The sequence of the A (or alanine) version is shown. The S (or serine) version differs in only two positions, and the K version in only one. There may be other versions in addition to the S, A, and K versions.
Similarity: Belongs to the telombin family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.